Pharmaceutics-I MCQ Type Question and Answer For D.Pharma

Pharmaceutics MCQ Questions – Pharmaceutics is the discipline of pharmacy that deals with all facets of the process of turning a new chemical entity (NCE) into a safe and effective medication. Pharmaceutics is the science of dosage form design. Pharmaceutics deals with the formulation of a pure drug substance into a dosage form.

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Table of Contents

Pharmaceutics – I (Theory and Practical)
Pharmaceutical Chemistry (Theory and Practical)
Pharmacognosy (Theory and Practical)
Biochemistry and Clinical Pathology (Theory and Practical)
Human Anatomy and Physiology (Theory and Practical)
Heath Education and Community Pharmacy (Theory)

Pharmaceutics – I (Theory and Practical) MCQ QUESTIONS

Which of the following gelatine concentration is used to determine the viscosity of gelatine used
for the preparation of soft gelatine capsules?
A. 6 2/3 %
B. 7 2/3%
C. 5 2/3 %
D. 6 3/4%
Ans. A
Measurement of particle size in pharmaceutical aerosol is by
(P) Cascade impactor (Q) Light scatter decay (R) K-F method (S) IR
A. Q, R
B. R, S
C. P, S
D. P, Q
Ans. D
Department of Transport Test (DOT) is performed for which of the following?
A. Aerosols
B. Glass containers
C. Capsules
D. None
Ans. A
The first aerosol insecticide was developed by
A. Good-hue & Sullivan
B. Good-hue
C. Sullivan
D. Franklin
Ans. A
Identify the correct non-flammable propellant
A. Dichloro monofluoro methane
B. Trichloro monofluoro methane
C. Di methyl ether
D. Di fluoro methane
Ans. B
According to Drugs and Cosmetics act, List of substances that should be sold by retail only on
prescription of registered medical practitioner is given in which of the following Schedule?
A. Schedule ‘H’
B. Schedule ‘V’
C. Schedule ‘X’
D. Schedule ‘Q’
Ans. A
The first pharmaceutical aerosol was developed in the year of
A. 1945
B. 1955
C. 1949
D. 1960
Ans. B
Which drug is formulated as first pharmaceutical aerosol?
A. Epinephrine
B. Codeine
C. Chloropromazine
D. Probenecid
Ans. A
The dip tube in an aerosol container is made from one of the following
A. Poly propylene
B. Glass
C. Al
D. Stainless steel
Ans. A
To dispense inhalation aerosols, which containers are used?
A. Stain less steel containers
B. Tin plate containers
C. Glass containers
D. Al containers
Ans. A
Which one of the following device is used to increase the efficiency of drug delivery via aerosols?
A. Tube spacers
B. Metered valves
C. Actuator
D. Pressure valve
Ans. B
The valve body /housing in a aerosol bottle valve assembly, is made from one of the following
A. Poly propylene
B. Poly ethylene
C. Nylon
D. Stain less steel
Ans. C
Among the propellants used in aerosols, one of the following is used for topical pharmaceutical aerosols
A. Tri chloro monofluoro methane
B. Di chloro difluoro methane
C. Di chloro tetrafluoro ethane
D. Propane
Ans. D
Which one of the following propellant is used in the aerosol for oral use
A. Propane
B. Oxygen
C. Trichloro monofluoro methane
D. Methane
Ans. C
The identification of propellants in pharmaceutical aerosols is carried out by
(P) Gas chromatography (R) Pycnometer (Q) Tag open cup apparatus (S) IR spectrophotometer
A. P,Q
B. P,S
C. Q, R
D. R, S
Ans. B
Aerosol packaging container mustresist pressure of
A. 500 psig
B. 140-180 psig
C. 40 psig
D. 20 psig
Ans. B
Manufacturing of aerosol involves
A. Gas filling
B. Pressure filling
C. Compressed gas filling
D. All the above
Ans. C
Gasket is made up of
A. Bure-N
B. Neoprene rubber
C. Both
D. Non of above
Ans. C
The nature of propellant is determined by
A. R-F method
B. Gas Chromatography
C. UVD.
D. None
Ans. B
Which of the following one is used to adjust the isotonicity
A. Dextrose
B. Boric acid
C. NaCl
D. All the above
Ans. D
Opthalmic solution is sterilized by
A. Autoclave
B. Hot air oven
C. Membrane filter
D. Bacterial filters
Ans. A
Ph of human tear is
A. 7.6
B. 4.5
C. 7.2
D. 9
Ans. A
Viscosity enhancer in ophthalmic preparation is
A. Poly vinyl alcohol
B. Povidone
C. Dextran
D. Macrogol
Ans. D
The ability of a substance dissolves in a given solvent system is depends on
A. Nature and intensity of the forces present in the solute
B. Nature and intensity of the forces present in the solvent
C. Interactions between solute and solvent
D. All the above
Ans. A
Which of the following substances having poor water solubility
A. Weak electrolytes
B. Non-polar molecules
C. Both
D. None
Ans. C
How co-solvents increase the solubility of poorly soluble drugs?
A. By reducing the interfacial tension between the predominant aqueous solution and
hydro- phobic solute
B. By reducing the interfacial tension between solute and solvent
C. Both
D. None
Ans. A
The solubility of weak electrolytes &non-polar substances can be increased by
adding water miscible solvents. This process is known as
A. Co-solvency
B. Complexation
C. Both
D. None
Ans. A
Which of the following co – solvents are used to increase the solubility of a drug
A. Ethanol
B. Sorbitol
C. Glycerin
D. All the above
Ans. D
Which of the following co – solvent is accepted as a co – solvent in
parenteral products, but its use in oral liquids is limited
A. Glycerol formal
B. Glycerol
C. Dimethyl acetamide
D. None
Ans. C
Due to which factor, dimethyl aceta-mide is not been used as a co-solvent in oral liquids
A. Due to objectionable odor
B. Due to objectionable taste
C. Both
D. None
Ans. C
Thiomersal is belongs to which category preservative
A. Acidic
B. Mercurial
C. Neutral
D. Quaternary ammonium compounds
Ans. B
At which concentration, phenol act as preservative
A. 0.2 – 0.5
B. 0.5 – 0.8
C. 0.05 – 0.1
D. None
Ans. A
Benzalkonium chloride is categorized as
A. Acidic preservative
B. Neutral preservative
C. Mercurial preservative
D. Quaternary ammonium compounds
Ans. D
Which of the following are widely used and excellent preservatives
A. Quaternary ammonium compounds
B. Mercurial
C. Both
D. Acidic
Ans. A
Which of the following is a synthetic sweetener
A. Glucose
B. Sucrose
C. Sorbitol
D. Aspartame
Ans. D
Which of the following sugar has bitter taste
A. Glucose
B. Sucrose
C. Saccharine
D. None
Ans. C
To increase the viscosity of liquid, which of the following agents are used
A. PVP
B. Methyl Cellulose
C. Sodium Carboxy Methyl Cellulose
D. All the above
Ans. D
Which of the following agents are used as flavoring agents
A. Menthol
B. Chloroform
C. Both
D. None
Ans. C
Most widely used flavoring agent in food industry
A. Menthol
B. Chloroform
C. Mono sodium glutamate
D. None
Ans. C
Which of the following flavor is not responsible for sour taste
A. Citrus flavors
B. Liquorice
C. Raspberry
D. Mint spice
Ans. D
Which of the following methods are generally used in liquid filling
A. Gravimetric
B. Volumetric
C. Constant level method
D. All the above
Ans. D
The filling method of a pharmaceutical liquid depends on the following factors
A. Viscosity of the liquid
B. Surface tension of the liquid
C. Compatibility with the materials used in the construction of the filling machine D. All the above
Ans. D
In the formulation of suspensions, generally which types of drugs areselected?
A. Hydrophilic
B. Hydrophobic
C. Both
D. None
Ans. B
In the formulation, to facilitate the wetting of insoluble solids, which of the following agents
used
A. Suspending agents
B. Wetting agents
C. Flavoring agents
D. None
Ans. B
How surfactants will facilitate or aid wetting of hydrophobic materials in liquid

A. By decreasing the solid-liquid interfacial tension
B. By increasing the solid-liquid interfacial tension
C. Both
D. None
Ans. A

To identify the emulsion type, which of the following tests are conducted?
A. Dilution test
B. Dye test
C. Conductivity test
D. All
Ans. D
The stability of suspensions can be evaluated by
A. Sedimentation volume
B. Degree of flocculation
C. Re-dispersibility
D. All
Ans. D
Stoke’s equation is expressed as
A. V = 2r2(d1–d2)g/18η
B. V = 2r2(d1–d2)g/9η
C. Both
D. None
Ans. B
The temperature at which the inversion occurs depends on emulsifier concentration is known
as
A. Phage temperature
B. Inversion temperature
C. Phase inversion temperature
D. All
Ans. D
Which of the following mechanical equipment can be used for emulsification?
A. Homogenizers
B. Mechanical stirrers
C. Ultrasonifiers
D. All
Ans. D
Which of the following is not used as a emulsifying agent?
A. Surfactant
B. Hydrophilic colloids
C. Electrolytes
D. Finely divided solids
Ans. C
HLB system was developed by
A. Griffin
B. Stock’s
C. Dalla Valle
D. None
Ans. A
Gum Arabic is a
A. Anionic polysaccharide
B. Cationic polysaccharide
C. Neutral polysaccharide
D. None
Ans. C
Which of the following is not a semisolid dosage form
A. Paste
B. Creams
C. Ointments
D. Suspensions
Ans. D
Generally pastes contain
A. High percentage of insoluble solids
B. Low percentage of insoluble solids
C. Both
D. None
Ans. A
Most widely used hydrocarbon in semisolid dosage forms
A. Petrolatum
B. Mineral oil
C. Both
D. None
Ans. C
Which of the following hydrocarbon waxes are employed in the manufacture of creams and
ointments?
A. Paraffin wax
B. Ceresin
C. Both
D. None
Ans. C
Which of the following is not a vegetable oil
A. Peanut oil
B. Almond oil
C. Olive oil
D. Petrolatum
Ans. D
Promulgen D contains
A. Cetyl alcohol & Ceteareth-20
B. Stearyl alcohol & Ceteareth-20
C. Both
D. None
Ans. A
Promulgen G contains
A. Cetyl alcohol & Ceteareth-20
B. Stearyl alcohol & Ceteareth-20
C. Both
D. None
Ans. B